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Description
Daiichi Sankyo Clean Dental N — 10-Ingredient Medicated Toothpaste, 50 g
Clean Dental N by Daiichi Sankyo Healthcare is a 医薬部外品 (quasi-drug) medicated toothpaste born from the research laboratories of one of Japan's leading pharmaceutical companies. Unlike cosmetic toothpastes, Clean Dental N incorporates 10 therapeutic active ingredients in a single tube — each targeting a specific aspect of oral health, from cavity prevention and gum disease to tartar inhibition and bad breath. It is the comprehensive oral care solution trusted by Japanese dentists and pharmacists.
See also: Oral Care | Japanese Health Products
Key Benefits
- ✓ Fluoride (sodium fluoride) — remineralises enamel and provides proven protection against cavities; the gold standard in cavity prevention
- ✓ ε-Aminocaproic acid — anti-inflammatory active that suppresses gum bleeding and gingivitis progression
- ✓ β-Glycyrrhetinic acid — licorice-derived anti-inflammatory; calms gum swelling and redness
- ✓ Cetylpyridinium chloride (CPC) — antibacterial quaternary ammonium compound; reduces oral bacteria load including plaque-forming Streptococcus mutans
- ✓ Sodium chloride (salt) — traditional Japanese oral care ingredient; stimulates gingival microcirculation and strengthens gum tissue
- ✓ Allantoin — promotes mucosal healing; soothes mouth ulcers and inflamed gum tissue
- ✓ Tocopherol acetate (Vitamin E) — antioxidant that protects gum cells from oxidative damage
- ✓ Zeolite — micro-polishing mineral that removes surface stains without abrasive damage to enamel
- ✓ Lauroyl sarcosine sodium (LSS) — antibacterial active that inhibits bacterial adhesion to tooth surfaces
- ✓ Daiichi Sankyo pharmaceutical backing — a company with decades of periodontal disease research behind this formulation
Product Details
| Detail | Information |
|---|---|
| Brand | Clean Dental (Daiichi Sankyo Healthcare) |
| Country of Origin | Japan |
| Product Type | Medicated Toothpaste |
| Format | Paste (tube, 50 g) |
| Volume / Weight | 50 g |
| JAN Code | 4903301241434 |
| Classification | 医薬部外品 (Quasi-drug, MHLW-approved) |
| Fluoride | Sodium fluoride (高濃度 / standard concentration) |
Who Is This For?
- ✓ Adults seeking total oral health management — one toothpaste addressing cavities, gum disease, tartar, bad breath, and whitening simultaneously
- ✓ People with bleeding gums or early gingivitis — ε-aminocaproic acid and β-glycyrrhetinic acid target the inflammatory component of gum disease
- ✓ High-cavity-risk individuals — frequent sugar consumers, those with previous dental history, or dry-mouth sufferers who need high-efficacy fluoride protection
- ✓ Japanese oral care enthusiasts — Clean Dental is a benchmark in the Japanese pharmaceutical-grade oral care category, recommended by Japanese dentists
- ✓ Adults 30+ managing long-term gum health — periodontal disease risk increases with age; Clean Dental N's multi-active approach provides preventive maintenance
How to Use
- Apply a pea-sized amount (approximately 1–1.5 cm) of Clean Dental N to a soft or medium toothbrush.
- Brush for at least 2 minutes, covering all tooth surfaces including the gum line — use the Bass technique (angled at 45° to the gumline) for gum care.
- Spit out the toothpaste. To maximise fluoride retention, spit without rinsing, or rinse with minimal water (one small rinse only) — rinsing completely with water dilutes fluoride efficacy.
- For supplementary gum care, use an interdental brush or floss before brushing.
Frequency: 2–3 times daily, after meals and before bed. The bedtime brush is most critical as saliva production drops during sleep, reducing natural enamel protection.
Active Ingredients
10 Therapeutic Active Ingredients (医薬部外品有効成分):
- Sodium fluoride (フッ化ナトリウム) — enamel remineralisation, cavity prevention
- ε-Aminocaproic acid (ε-アミノカプロン酸) — anti-inflammatory, anti-gingivitis, reduces gum bleeding
- β-Glycyrrhetinic acid (β-グリチルレチン酸) — licorice-derived anti-inflammatory, calms inflamed gums
- Cetylpyridinium chloride (CPC / 塩化セチルピリジニウム) — broad-spectrum antibacterial, kills oral pathogens
- Sodium chloride (塩化ナトリウム) — gum stimulation, increases blood flow to periodontal tissue
- Allantoin (アラントイン) — tissue repair, anti-inflammatory for mucosal healing
- Tocopherol acetate (酢酸トコフェロール) — Vitamin E, antioxidant protection for gum cells
- Zeolite (ゼオライト) — gentle micro-polishing, tartar and stain control
- Lauroyl sarcosine sodium (ラウロイルサルコシンナトリウム / LSS) — bacteriostatic, prevents bacterial adhesion to enamel
- Tranexamic acid (トラネキサム酸) (if N-series variant contains it) or additional anti-bleeding agent depending on specific formulation
Full ingredient list on product packaging. Clean Dental N is free from saccharin. Consult the label for complete composition and preservative details.
Cautions
- Keep out of reach of young children. Fluoride-containing toothpastes should not be swallowed in large amounts — children under 6 should use a children's fluoride toothpaste at lower fluoride concentration.
- For external use (oral cavity) only. Do not swallow.
- If gum pain, swelling, or bleeding does not improve after 2 weeks of consistent use, consult a dentist — these may indicate deeper periodontal disease requiring professional treatment beyond toothpaste.
- Consult a dentist before use if you have severe dental sensitivity, known oral mucosal conditions, or allergy to any listed ingredient.
- Store at room temperature away from direct heat and sunlight.
- Note: This product is a preventive oral care aid — not a substitute for regular dental check-ups and professional cleaning (every 6 months minimum).
Package Contents
- 1 × Clean Dental N Medicated Toothpaste, 50 g tube
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics and supplements cannot be returned for hygiene and safety reasons
Authenticity Guarantee
All Daiichi Sankyo Healthcare products at Tsujimoto Market are sourced directly from authorised Japanese distributors and shipped from our warehouse in Kobe, Japan. Clean Dental N is the same pharmaceutical-grade quasi-drug sold in Japanese pharmacies — you receive full Japanese market quality. Trusted Since 2015.
Frequently Asked Questions
What makes Clean Dental N different from ordinary toothpastes?
Most mass-market toothpastes focus on 1–3 active ingredients (typically fluoride + whitening abrasive + flavour). Clean Dental N is classified as a 医薬部外品 (quasi-drug) under Japanese pharmaceutical law — meaning it contains 10 MHLW-regulated active ingredients at clinically relevant concentrations for preventing gum disease, cavities, tartar, and bad breath simultaneously. It was developed from periodontal disease research by Daiichi Sankyo Healthcare, a pharmaceutical company rather than a consumer goods company, which reflects in the depth of the formulation.
Should I rinse with water after brushing with Clean Dental N?
For maximum cavity prevention, dental researchers recommend not rinsing (or minimal rinsing with a small amount of water) after brushing with fluoride toothpaste. Rinsing immediately with a full glass of water washes away most of the fluoride before it can be absorbed into enamel. The Japanese dental guideline promoted by Daiichi Sankyo is: brush → spit → do not eat or drink for 30 minutes. This maximises the fluoride remineralisation window.
Is Clean Dental N suitable for sensitive teeth?
Clean Dental N is a gum-disease-focused multi-active formula rather than a desensitisation toothpaste. If your primary concern is sensitivity (sharp pain to cold, hot, or sweet), a toothpaste containing potassium nitrate or stannous fluoride specifically for hypersensitivity would be more targeted. However, many users with mild sensitivity find the anti-inflammatory actives (β-glycyrrhetinic acid, ε-aminocaproic acid) in Clean Dental N indirectly help by reducing gum recession-related sensitivity over time. For severe sensitivity, consult a dentist.
What is the difference between Clean Dental N and Clean Dental L or Clean Dental Premium?
The Clean Dental range from Daiichi Sankyo includes several variants targeting different priorities: Clean Dental N (this product) is the comprehensive 10-ingredient standard formula. Clean Dental L Total Care is designed for all-around oral care with a slightly different active ingredient combination. Clean Dental Premium targets advanced gum care with a higher concentration of anti-inflammatory actives. For general preventive care, Clean Dental N is the most balanced starting point. Your dentist can advise which variant is most appropriate for your specific oral health profile.
How do I store Clean Dental N toothpaste?
Store at room temperature in a dry place away from direct sunlight and extreme heat (avoid leaving in a hot car or bathroom with direct sun exposure). Keep the cap tightly closed after each use to prevent the paste from drying out and to maintain the stability of active ingredients. Fluoride and CPC can degrade over time if exposed to heat and humidity. The tube is designed for efficient single-use dispensing; squeezing from the bottom up prolongs even product delivery.
