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Description
Hada Labo Shirojun Premium Medicated Whitening Lotion (Moist), 170 ml
Overview
Shirojun Premium (肌ラボ 白潤プレミアム 薬用浸透美白化粧水 しっとり) is the upper tier of Rohto's Hada Labo brightening line — the deep blue bottle. It is a Japanese quasi-drug with two approved actives: tranexamic acid for preventing spots and freckles caused by sun exposure, and dipotassium glycyrrhizate for preventing rough, irritated skin. Around them sit two hyaluronic acids, a vitamin C derivative and vitamin E. The texture is the moist (しっとり) type: a lightly thickened, watery lotion with no fragrance.
This listing is the Premium version. The standard Shirojun lotion (one active, lighter blue bottle) is a different product; we list it separately as Hada Labo Shirojun Medicated Whitening Lotion Rich. See also our Japanese toners and brightening skincare collections.
Key Benefits
- ✓ Two approved quasi-drug actives: tranexamic acid (whitening) and dipotassium glycyrrhizate (anti-inflammatory)
- ✓ Prevents new spots and freckles from forming after sun exposure
- ✓ Calms rough, irritated skin — irritation itself can drive pigmentation
- ✓ Two hyaluronic acids, vitamin C derivative and vitamin E for hydration and conditioning
- ✓ Fragrance-free and colourant-free
- ✓ Bought in Japan and shipped from Kobe with tracking
Product Details
| Brand | Hada Labo (Rohto Pharmaceutical) |
|---|---|
| Product name (JP) | 肌ラボ 白潤プレミアム 薬用浸透美白化粧水 しっとり |
| Product type | Medicated whitening lotion / toner |
| Texture | Moist (しっとり) |
| Volume | 170 ml |
| JAN code | 4987241168491 |
| Regulatory status | Quasi-drug (医薬部外品) in Japan |
| Scent | Fragrance-free |
| Country of origin | Japan |
Who Is This For?
- Skin with sun-related discolouration, post-acne marks or uneven tone
- Anyone who wants a brightening toner that does not sting — no acids, no fragrance
- Skin that gets red or rough easily and needs calming as well as brightening
- Those already using a daily sunscreen, which is the condition under which this product makes sense
- Not for you if you want removal of an established, well-defined age spot — that is a dermatology conversation
How to Use
- After cleansing, pour a suitable amount into your palm.
- Press it over the whole face with your palms.
- Go over areas of concern with a second, thinner layer.
- Follow with emulsion or cream; in the morning, finish with sunscreen SPF 30 or higher.
Frequency: morning and evening. Judge results at eight to twelve weeks, not at two.
Full Ingredients
Active ingredients (quasi-drug): tranexamic acid, dipotassium glycyrrhizate.
Other ingredients: hydrolyzed hyaluronic acid (nano hyaluronic acid), sodium hyaluronate-2, magnesium ascorbyl phosphate (vitamin C derivative), vitamin E, BG, concentrated glycerin, diglycerin, pentylene glycol, PEG(30), PEG-8, POE(24)POP(24) glyceryl ether, edetate, POE(20) sorbitan laurate, VP/styrene copolymer emulsion, sodium metabisulfite, carboxyvinyl polymer, phenoxyethanol.
Ingredient list as declared by the manufacturer. Formulations are occasionally revised, so always read the list printed on the package you receive.
Cautions
- This is a Japanese quasi-drug (医薬部外品): the active ingredients and the effect claimed for them have been reviewed by Japan's Ministry of Health, Labour and Welfare. Outside Japan it is sold as an ordinary cosmetic.
- This product contains no sun filters — apply sunscreen separately.
- The approved claim is prevention of spots and freckles caused by sun exposure, not removal of existing pigmentation.
- If redness, swelling, itching, irritation, loss of pigment or darkening appears during or after sun exposure, stop using it and consult a dermatologist.
- Do not use on wounds, swelling, eczema or other damaged skin.
- Avoid contact with the eyes; if it gets into the eyes, rinse immediately with water.
- Keep out of reach of children. Store away from direct sunlight and high temperatures.
Package Contents
- 1 × Hada Labo Shirojun Premium Medicated Whitening Lotion (Moist), 170 ml bottle
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics cannot be returned for hygiene and safety reasons
Authenticity Guarantee
Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed in Kobe, Japan and dispatched with full tracking.
FAQ
Is this the Premium version?
Yes. This listing is Shirojun Premium, the version with two actives (tranexamic acid and dipotassium glycyrrhizate). The standard Shirojun lotion has tranexamic acid with a different second active and is listed separately on our site.
Does tranexamic acid block tyrosinase?
No. Tyrosinase inhibitors such as arbutin or kojic acid interrupt the enzyme that builds melanin. Tranexamic acid works one step earlier, on the inflammatory signalling that tells pigment cells to switch on after UV exposure. That is why it is associated with diffuse, blotchy discolouration rather than a single sharp-edged sun spot.
How long before I see anything, and will dark spots disappear?
Give it eight to twelve weeks of twice-daily use before you judge it. Products in this category make marks look lighter and stop new ones from darkening — they do not erase established pigmentation. If nothing has shifted after three months, a dermatologist has options a toner does not.
The packaging is in Japanese — how do I know what I am using?
This is stock made for the Japanese domestic market, so the bottle carries Japanese-language labelling. The ingredient list above is translated from the manufacturer's declaration. Send us a photo of anything unclear after delivery and we will translate it.
Will I pay customs duty or import VAT?
That depends on your country and on the declared value of the parcel. We ship from Japan with a correct customs declaration and full tracking; any duty or import VAT your country charges is collected by your local carrier or customs office on delivery.



