Tsujimoto Market: Our Guarantees
Description
SANA Nameraka Honpo Medicated Wrinkle Night Cream White 50 g – Japanese Quasi-Drug
Overview
Nameraka Honpo is Tokiwa Pharmaceutical's soy-milk line, and this is the night cream at the top of its Wrinkle White branch. It is a quasi-drug (医薬部外品), and the approved active (有効成分) is niacinamide — one of the few ingredients Japan allows to claim wrinkle improvement rather than merely the appearance of it.
The maker's own two-part claim is worth quoting because the boundary between its halves is exactly where most pages go wrong. Niacinamide reaches the dermis, promotes collagen production and improves wrinkles; and separately it suppresses melanin production and prevents spots and freckles. Prevention, not removal. Nothing in a Japanese quasi-drug approval covers fading a mark you already have, and this page does not say otherwise.
Around the active sit pure retinol and a fermented soy milk liquid (豆乳発酵液) made from the Japanese soybean variety たまほまれ. The texture is an おやすみパック処方 — an overnight-pack formulation that sets into a breathable film rather than staying slippery, which is why it does not end up on the pillowcase.
See also our Japanese face creams and the wider anti-ageing range.
Key Benefits
- ✓ Quasi-drug (医薬部外品) whose approved active is niacinamide, carrying a wrinkle-improvement claim
- ✓ The maker's mechanism: niacinamide reaches the dermis and promotes collagen production
- ✓ Second approved claim, kept separate: suppresses melanin production to prevent spots and freckles
- ✓ Pure retinol and fermented soy milk liquid from the Japanese soybean たまほまれ alongside the active
- ✓ Overnight-pack formulation (おやすみパック処方) that sets rather than staying slippery
- ✓ Fragrance-free, colourant-free and mineral-oil-free by the maker's declaration (無香料・無着色・無鉱物油)
- ✓ 50 g jar, ceramide NP and sugar squalane in support, JAN 4964596701900, shipped from Kobe
Product Details
| Brand | SANA Nameraka Honpo (Tokiwa Pharmaceutical Co., Ltd.) |
|---|---|
| Japanese name | なめらか本舗 薬用リンクルナイトクリーム ホワイト |
| Sales name (販売名) | サナ なめらか本舗 薬用リンクルナイトクリーム ホワイト f |
| Japanese product class | Quasi-drug (医薬部外品) |
| Approved active (有効成分) | Niacinamide |
| Approved claims | Improves wrinkles; suppresses melanin production to prevent spots and freckles |
| Other notable ingredients | Pure retinol; fermented soy milk liquid; ceramide NP; sugar squalane; licorice root extract |
| Size | 50 g |
| Form | Overnight-pack cream |
| Fragrance / colourant / mineral oil | None added (無香料・無着色・無鉱物油) |
| Contains | Ethanol and phenoxyethanol |
| JAN | 4964596701900 |
Who Is This For?
- Skin where both concerns are present at once — set lines and uneven tone — and you would rather not run two separate night products
- Anyone who wants a wrinkle claim that is actually approved rather than implied; in Japan that means a quasi-drug, and this is one
- People starting retinol who want it at a cosmetic strength buffered by a rich overnight base
- Side sleepers, because the overnight-pack texture sets instead of transferring
- Not the product if your aim is fading marks you already have — this formula is approved to prevent them, not remove them
- Introduce carefully if you are new to retinol, and see the cautions on pregnancy below
How to Use
- Use it last in the evening routine, after your toner and emulsion.
- Take a pearl-sized amount and warm it briefly between the fingers.
- Press it over the whole face in light upward strokes rather than rubbing it in.
- Pat gently to help it settle; the overnight-pack texture is meant to set into a film.
- Carry the same amount down the neck if you are treating lines there too.
Frequency: Once nightly. Morning use is possible with a smaller amount, though the overnight-pack film can unsettle makeup.
Full Ingredients
Approved active (有効成分): niacinamide.
Other ingredients (その他の成分): water, BG, concentrated glycerin, sugar squalane, octyldodecyl myristate, dimethicone, batyl alcohol, hydrogenated oil, stearic acid, polyglyceryl-2 distearate, glyceryl stearate SE, dipentaerythrityl fatty acid esters, behenyl alcohol, fermented soy milk liquid, retinol oil liquid, N-stearoyl dihydrosphingosine (ceramide NP), ethanol, carbomer, licorice root extract, xanthan gum, sorbitol fermented polysaccharide, soybean extract, betaine, phytosterol, decaglyceryl monomyristate, potassium hydroxide, sodium hydroxide, hydrogenated soy lecithin, phenoxyethanol.
Two things in that list are worth naming plainly rather than leaving for you to spot. It contains ethanol, which the maker's no-fragrance, no-colourant, no-mineral-oil declaration does not cover, and it contains soybean-derived material in three places — the fermented soy milk, the soybean extract and the hydrogenated soy lecithin — which matters if soy is one of your allergens.
Cautions
- For external use only. Patch-test on the inner wrist 24 hours before the first full use.
- Stop at once and see a dermatologist if redness, itching or irritation appears.
- Do not apply to broken, wounded or badly irritated skin.
- Keep out of the eyes; rinse with plenty of water if it gets in.
- This contains retinol. If you are pregnant or breastfeeding, speak to your doctor before using a retinol product; many clinicians advise against topical retinoids during pregnancy.
- New to retinol? Expect a possible fortnight of mild tingling or dryness, and drop to every other night if it appears.
- Contains ethanol and soybean-derived ingredients — check the list above if either is a problem for you.
- Quasi-drug status (医薬部外品) is a Japanese classification and may not carry over to your country. Store away from direct sun, heat and humidity, out of reach of children.
Package Contents
One 50 g jar with an inner lid. No spatula is included; use clean fingers or your own spatula, and close the inner lid each time — the retinol and the fermented liquid both keep better away from air.
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics cannot be returned for hygiene and safety reasons
Authenticity Guarantee
Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed in Kobe, Japan and dispatched with full tracking.
FAQ
Will it fade the dark spots I already have?
No, and the approval does not say it will. The maker's melanin claim is that niacinamide suppresses melanin production and thereby prevents spots and freckles. That is a forward-looking claim about marks that have not formed yet. An existing mark is a different problem and usually a clinical one.
Is the wrinkle claim real or marketing?
It is a registered claim. Japan approves very few ingredients to say they improve wrinkles rather than soften their appearance, and niacinamide at quasi-drug concentration is one of them. That approval is why this product is 医薬部外品 rather than a cosmetic, and the maker states the mechanism as reaching the dermis and promoting collagen production.
Is it scented?
No. Tokiwa declares it 無香料 — fragrance-free — along with no colourant and no mineral oil. Our own page previously said it carried a light scent; that was wrong, and it has been corrected against the maker's declaration.
Can I use it with a vitamin C serum?
Yes, and at different times of day is the easiest way. Vitamin C in the morning and this cream at night avoids stacking two actives in one layer, and the retinol here belongs at night anyway. If you prefer both in the evening, leave the cream until last, as the instructions say.
Can I use it while pregnant?
Ask your doctor first. This cream contains retinol, and many clinicians advise avoiding topical retinoids in pregnancy and while breastfeeding. We would rather you check than have us reassure you about something that is a medical question and not a cosmetic one.





