Description
SANA Nameraka Honpo Medicated Wrinkle Night Cream White by Tokiwa Pharmaceutical is a Japanese quasi-drug (医薬部外品) overnight face cream that targets wrinkles and dark spots simultaneously. Powered by niacinamide as the active ingredient — approved in Japan for wrinkle improvement and melanin inhibition — plus pure retinol and a proprietary soy milk fermented extract, this cream works while you sleep to leave skin visibly firmer, more even-toned, and intensely moisturised by morning. Its overnight pack formulation adheres to the skin through the night without feeling sticky.
Key Benefits
- Niacinamide (active ingredient / 有効成分): penetrates to the dermis to stimulate collagen production, visibly reducing fine lines and wrinkles — approved quasi-drug claim in Japan
- Niacinamide also inhibits melanin transfer in the epidermis, helping to fade existing dark spots and prevent new spots and freckles from forming
- Pure retinol (保湿成分): works synergistically with niacinamide to promote skin cell turnover and improve elasticity and firmness
- Soy milk fermented extract (豆乳発酵液): rich in isoflavones and amino acids for aging-appropriate (エイジングケア) moisturisation and suppleness
- Overnight pack formulation: cream forms a breathable seal over the skin during sleep, locking in active ingredients and preventing moisture loss
- Non-sticky finish — does not transfer to pillows; morning skin feels plump, soft, and cushioned
Product Details
| Brand | SANA (サナ) by Tokiwa Pharmaceutical Co., Ltd. |
|---|---|
| Product Name (EN) | Nameraka Honpo Medicated Wrinkle Night Cream White |
| Product Name (JP) | なめらか本舗 薬用リンクルナイトクリーム ホワイト |
| Sales Name (JP) | サナ なめらか本舗 薬用リンクルナイトクリーム ホワイト ｆ |
| Category | Skincare |
| Subcategory | Moisturizer / Night Cream |
| Product Type | Overnight pack cream / face cream |
| Size / Net Content | 50g |
| Form | Cream |
| Fragrance / Scent | Light scent (not fragrance-free) |
| Regulatory Classification | Quasi-drug (医薬部外品) — Japan |
| Country of Origin | Japan |
| Skin Type / Target User | All skin types; particularly suited to those with signs of aging (wrinkles, dark spots), from late 20s onwards |
| Main Concerns | Wrinkles / fine lines, dark spots, uneven skin tone, dryness, loss of firmness |
| Key Ingredients | Niacinamide (active), Pure Retinol, Soy Milk Fermented Extract, Ceramide NP (N-Stearoyl Dihydrosphingosine), Sugar Squalane |
| SKU | Sana NaHoNW50 |
| JAN Code | 4964596701900 |
Who Is This For?
Recommended for adults from the late 20s upwards who are concerned about fine lines, wrinkles, or uneven skin tone including dark spots and freckles. Ideal if you want a single overnight step that addresses both anti-aging and brightening. Particularly effective when used as the final step in the Nameraka Honpo Wrinkle White system (after the medicated lotion and emulsion from the same range). Also suitable for use on the neck.
How to Use
Use as the last step of your evening skincare routine, after toner and emulsion. 1. Take a pearl-sized to pea-sized amount of cream into clean palms. 2. Warm between fingers for a moment to soften the texture. 3. Press and blend gently over the entire face in light, upward strokes. 4. Pat gently to aid absorption — do not rub. Amount: Approximately one pearl-sized amount per application. Frequency: Primarily once nightly. Morning use is possible but reduce the amount to avoid makeup breakdown. Tip: Extend application down the neck and décolletage for consistent anti-aging coverage.
Full Ingredients
Active ingredient (有効成分): Niacinamide (ナイアシンアミド). Other ingredients (その他の成分): Water, BG (Butylene Glycol), Concentrated Glycerin, Sugar Squalane, Octyldodecyl Myristate, Dimethicone (Methylpolysiloxane), Batyl Alcohol, Hydrogenated Oil, Stearic Acid, Polyglyceryl-2 Distearate, Glyceryl Stearate SE, Dipentaerythrityl Fatty Acid Esters, Behenyl Alcohol, Fermented Soy Milk Liquid (豆乳発酵液), Retinol Oil Liquid (レチノール油液), N-Stearoyl Dihydrosphingosine (Ceramide NP), Ethanol, Carbomer, Glycyrrhiza Glabra (Licorice) Root Extract, Xanthan Gum, Sorbitol Fermented Polysaccharide, Soybean Extract, Betaine (Trimethylglycine), Phytosterol, Decaglyceryl Monomyristate, Potassium Hydroxide, Sodium Hydroxide, Hydrogenated Soy Lecithin, Phenoxyethanol. Note: Formulation may be updated — always check the product label for the most current ingredient list.
Cautions
- For external use only
- Perform a patch test on the inside of your wrist 24 hours before first use — discontinue immediately if any redness, itching, or irritation occurs
- Do not use on broken, wounded, or severely irritated skin
- Avoid contact with eyes. If contact occurs, rinse immediately with plenty of water
- Keep out of reach of children
- Store away from direct sunlight, high temperature, and humidity
- Consult a dermatologist before use if you have a diagnosed skin condition
- This product is classified as a quasi-drug (医薬部外品) in Japan. Regulatory status may differ in your country
- Ingredient formulations may be updated — always check the product label for the most current ingredient list
Package Contents
- 1 × SANA Nameraka Honpo Medicated Wrinkle Night Cream White 50g
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics and supplements cannot be returned for hygiene and safety reasons
Authenticity Guarantee
Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed and dispatched with full tracking.
FAQ
Q: Can I use this cream in the morning as well as at night?
A: Yes — the product can be used in the morning, but the brand recommends being mindful of quantity as the overnight pack formulation may cause makeup to slide or break down more easily. It is primarily designed for nighttime use as the last step of your evening skincare routine.
Q: Is this suitable for sensitive skin?
A: The cream is formulated to be gentle and non-sticky, making it suitable for a wide range of skin types. However, it contains retinol and niacinamide, which some sensitive skin types may need to introduce gradually. A patch test is recommended before first full-face use.
Q: What does 'quasi-drug' (医薬部外品) mean on the label?
A: In Japan, quasi-drugs are a regulatory category between cosmetics and pharmaceuticals. Nameraka Honpo Wrinkle Night Cream White carries this status because niacinamide at effective concentrations is approved for wrinkle improvement and melanin-inhibiting claims in Japan. This is a mark of efficacy, not a drug that requires a prescription.
Q: Can retinol in this cream cause skin purging or sensitivity?
A: The concentration of pure retinol in this product is cosmetic-grade and designed for daily use. Some first-time retinol users may experience mild adjustment in the first 1–2 weeks (slight tingling or dryness). If this occurs, reduce frequency to every other night and build up gradually.
Q: Is this the authentic Japanese product?
A: Yes. Tsujimoto Market sources all products directly from Japan. This is the genuine SANA Nameraka Honpo product as sold in the Japanese domestic market, not a locally licensed version or reformulation.
Q: How long does shipping take and will I have to pay customs?
A: Orders are dispatched from Japan within 2–6 business days with full tracking. Import duties may apply depending on your destination country — please check local regulations before ordering.