Santen Sante FX Neo Cooling Eye Drops — Instant Relief for Eye Fatigue & Redness

Santen Sante FX Neo — Iconic Japanese Cooling Eye Drops for Instant Eye Fatigue Relief

Sante FX Neo by Santen Pharmaceutical is Japan's most iconic cooling eye drop — the silver bottle you'll find in every pharmacy from Tokyo to Osaka. Six active ingredients including neostigmine methyl sulfate, taurine, and L-aspartic acid potassium work together to promote eye tissue metabolism and relieve fatigue, while the signature powerful cooling sensation instantly refreshes and revitalises strained eyes. 12 ml. Ships directly from Japan.

Natalia's Note

"Sante FX Neo is THE eye drop that every tourist buys in Japan — and for good reason. The cooling sensation is unlike anything you've tried before. My husband uses it every day after work, and honestly, it's become a ritual. If you've never tried Japanese eye drops, this is the perfect first one. The 'wake up' effect is real — it's like splashing cold water on your eyes, but in a good way." — Natalia, Founder of Tsujimoto Market

Key Benefits

• ✓ Powerful instant cooling effect — Santen's strongest refreshing formula; d-borneol, dl-camphor, and l-menthol deliver an invigorating sensation that wakes up tired eyes in seconds
• ✓ Relieves eye fatigue at the source — neostigmine methyl sulfate improves the eye's focus adjustment function, directly addressing the strain caused by prolonged screen use, reading, or driving
• ✓ Promotes eye tissue metabolism — taurine (1.0%) and L-aspartic acid potassium (1.0%) actively support cellular recovery and oxygen supply in eye tissue
• ✓ Reduces redness — tetrahydrozoline hydrochloride constricts conjunctival blood vessels, clearing redness fast
• ✓ Soothes itching and inflammation — chlorpheniramine maleate blocks histamine action; epsilon-aminocaproic acid suppresses inflammatory substances in the eye
• ✓ Helps after UV exposure — soothes eyes irritated by sunlight, UV light, or reflective environments (snow, water)
• ✓ Japan pharmacy staple — the silver bottle beloved by millions; a must-buy for first-time visitors to Japan and a daily ritual for regulars
• ✓ Authentic Japanese pharmaceutical product — Santen Pharmaceutical, ships direct from Japan

Best For

• Digital eye strain from screens — computer work, smartphone use, gaming
• Students during long study sessions
• Drivers who need to stay alert and focused
• Anyone who loves a strong, invigorating cooling sensation
• Eyes irritated by dust, sweat, UV light, or swimming
• Hard contact lens wearers (remove lenses before use)

Indications

Eye fatigue, conjunctival redness, eye itching, prevention of eye disease (after swimming, or when dust or sweat enters the eye), eye inflammation caused by UV light or other light sources (such as snow blindness), eye haziness (when accompanied by discharge), blepharitis (eyelid irritation), discomfort from hard contact lens wear.

How to Use

1. Tilt your head back slightly and pull down the lower eyelid
2. Apply 2–3 drops into each eye
3. Blink gently to distribute the drops evenly

Frequency: 5–6 times daily
Contact lenses: Remove hard contact lenses before use. Wait a few minutes before reinserting.
Tip: Refrigerate the bottle before use for an even more intense cooling effect — a popular trick in Japan during summer.

Active Ingredients

Ingredient	Concentration	Action
Neostigmine Methyl Sulfate	0.005%	Improves focus adjustment function; relieves eye fatigue
Taurine	1.0%	Promotes eye tissue metabolism
L-Aspartic Acid Potassium	1.0%	Enhances cellular respiration in eye tissue
Tetrahydrozoline Hydrochloride	0.05%	Constricts conjunctival blood vessels; reduces redness
Chlorpheniramine Maleate	0.03%	Blocks histamine; reduces eye inflammation and itching
Epsilon-Aminocaproic Acid	1.0%	Suppresses production of inflammatory substances

Inactive ingredients: Chlorobutanol, benzalkonium chloride, boric acid, d-borneol, dl-camphor, l-menthol, pH adjusters.

Cautions

• For ophthalmic (eye) use only.
• Remove hard contact lenses before use. Wait several minutes before reinserting.
• Not for use with soft contact lenses.
• Do not use if the solution has changed colour or become cloudy.
• Do not touch the dropper tip to any surface, including the eye, to avoid contamination.
• Do not use if you are sensitive to any of the active or inactive ingredients.
• Consult a doctor before use if you have glaucoma or are under medical treatment for an eye condition.
• If irritation, pain, or vision changes occur or persist after use, discontinue and consult an ophthalmologist.
• Keep out of reach of children.
• Store away from direct sunlight and heat. Refrigeration is acceptable.
• Use within the period indicated on the packaging after opening.

Package Contents

• 1 × Sante FX Neo eye drops — 12 ml

Shipping & Store Notes

• Ships directly from Japan
• Processing time: 2–6 business days
• Tracking number provided after dispatch
• Import duties and taxes may apply depending on destination country
• Opened eye drops cannot be returned for hygiene and safety reasons

Authenticity Guarantee

Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed and dispatched with full tracking.