Tsujimoto Market: Our Guarantees
Description
Spa Treatment exo Moist Essence — Emulsion-Type Essence with Exosomes, 30 ml
Overview
A rich, emulsion-type essence — the manufacturer classes it as a nyuueki (milk-type) product, meaning it sits closer to a milk than to a watery serum. Alongside the exosome fraction it carries a genuinely active supporting cast: niacinamide, retinol, squalane, hyaluronic acid, β-glucan and several plant oils.
Spa Treatment is a professional skincare line from the Japanese manufacturer Wave Corporation, sold mainly through salons and aesthetic clinics in Japan. The eX range is its salon-grade tier. Two things about this product matter more than the marketing: the exosomes are derived from human cells, and the formula contains retinol. Both change who should use it and how. We have put both in Cautions rather than leaving them in a list of ingredients.
See also our Japanese serums and anti-ageing care collections.
Key Benefits
- ✓ Emulsion-type texture — a moisturising step and an essence in one, useful for dry skin
- ✓ Niacinamide (vitamin B3), one of the best-tolerated actives in skincare
- ✓ Retinol included, so this is a genuine active product rather than a hydrating essence alone
- ✓ Squalane, hyaluronic acid and β-glucan as humectants and emollients
- ✓ Salon-tier Japanese formulation in a compact 30 ml bottle
- ✓ Human-origin, nut and retinol facts stated up front so you can decide before you buy
Product Details
| Brand | Spa Treatment (Wave Corporation) |
|---|---|
| Country of origin | Japan |
| Product type | Essence / emulsion |
| Format | Emulsion-type essence |
| Volume | 30 ml |
| Contains retinol | Yes |
| Ingredient of human origin | Yes — human adipose stromal cell exosomes |
| Tree nut | Yes — sweet almond oil |
| Quasi-drug status | Cosmetic (not a quasi-drug, iyakubugaihin) |
| Vendor | Tsujimoto Market, Kobe, Japan |
Who Is This For?
- Dry to normal skin that wants one richer step rather than several thin layers
- People already comfortable with retinol who want it in a moisturising base
- Not for anyone pregnant or breastfeeding — this contains retinol
- Not for anyone with a tree-nut allergy — this contains almond oil
- Not for anyone avoiding human-derived ingredients, or ordering into the EU — see Cautions
How to Use
- Use in the evening, after cleansing and lotion.
- Dispense about half a pipette or a small pea-sized amount.
- Warm between the fingertips, then press gently over the face — do not rub retinol products in hard.
- Start with two or three evenings a week and build up only if your skin stays comfortable.
- Follow with a cream if you need it, and use a broad-spectrum sunscreen every morning while you are using this product.
Frequency: Evenings only, starting at two to three times a week. Retinol and morning sun do not mix well.
Full Ingredients
Manufacturer's declared components: human adipose stromal cell exosome conditioned extract, niacinamide, squalane, olive oil, sweet almond oil, jojoba seed oil, retinol, hyaluronic acid, β-glucan, methionine (used to stabilise the exosome fraction).
The brand does not publish a complete Latin-script INCI for this product, so treat the above as the declared actives rather than a full ingredient list. The complete list is printed on the carton.
Origin flags: the exosome fraction is human-derived (see Cautions and FAQ). Sweet almond oil is a tree-nut ingredient. Retinol carries its own precautions, set out below.
Ingredient list as declared by the manufacturer. Formulations are occasionally revised, so always read the list printed on the package you receive.
Cautions
- Contains an ingredient derived from cultured human cells. Ingredients of human origin are not permitted in cosmetics sold in the European Union (Regulation (EC) No 1223/2009, Annex II). This is a Japanese domestic cosmetic and is offered on that basis; if you are ordering into the EU, please read the FAQ below before you buy.
- Contains retinol. Do not use if you are pregnant, planning pregnancy or breastfeeding. High-dose oral vitamin A is associated with birth defects, and the standard advice in pregnancy is to avoid topical retinoids as a precaution. Speak to your doctor or midwife.
- Retinol increases the skin's sensitivity to sunlight. Use a broad-spectrum sunscreen daily throughout the period you use this product, and for some weeks afterwards.
- Contains sweet almond oil — a tree nut. Do not use if you have a nut allergy.
- Do not layer with other retinoids, strong acids or benzoyl peroxide in the same routine unless a dermatologist has told you to. Mild dryness or flaking in the first fortnight is common; persistent burning is not.
- Patch test on the inner forearm before first use, especially if your skin is reactive.
- Discontinue use and consult a doctor if redness, itching, swelling or persistent stinging occurs.
- Avoid contact with the eyes. If the product enters the eyes, rinse immediately with plenty of water.
- Do not apply to broken, sunburned or actively inflamed skin.
- Keep out of reach of children. Store away from direct sunlight and high temperatures.
Package Contents
One 30 ml bottle of Spa Treatment exo Moist Essence in its Japanese retail carton. Labelling is in Japanese.
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics cannot be returned for hygiene and safety reasons
Authenticity Guarantee
Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed in Kobe, Japan and dispatched with full tracking.
FAQ
This contains a human-derived ingredient — what does that mean for me?
It means the active is grown from cultured human cells rather than from a plant or an animal. Japan permits this class of ingredient in cosmetics and regulates it; the European Union does not permit it at all, because Annex II of the EU Cosmetics Regulation prohibits cells, tissues and products of human origin in cosmetic products. That prohibition is about the risk of transmitting disease through human-sourced material, and it applies regardless of how the ingredient performs. Practically: this is a Japanese domestic product, we ship it as such, and an EU customs authority may take a view on it. It is also, unavoidably, neither vegan nor acceptable under most halal interpretations. If any of that is a problem for you, we would rather you knew before ordering than after.
What do exosomes actually do in a skincare product?
Exosomes are small vesicles that cells release, and in the body they do carry material between cells — that part is real biology. What is not established is that exosomes applied to intact skin in a cosmetic cross the skin barrier and go on to signal your own cells. The barrier is very good at keeping particles of that size out, which is largely the point of having one. So we describe this as a well-formulated moisturising essence that also contains niacinamide and retinol, both of which have solid evidence behind them, rather than repeating the cell-communication story the old description told.
Can I use this if I am pregnant?
No. It contains retinol, and the precautionary advice throughout pregnancy and breastfeeding is to avoid topical retinoids. If you want a Japanese anti-ageing serum without retinol, the Obagi Derma Power X Stem Lift Serum in our range is peptide-based and retinol-free.
The essence and the emulsion listings look the same — which do I want?
They describe the same formula. The manufacturer classes exo Moist Essence as an emulsion-type product (nyuueki), which is why both words appear. If you are unsure which listing size fits your routine, message us before ordering and we will confirm what is in stock.
Is this product halal or suitable for vegans?
Neither vegan nor suitable under most halal interpretations, because the exosome fraction is of human origin. The product carries no halal certification — Japanese domestic cosmetics are rarely certified — so if certification itself matters to you, this product does not have it.


