Description
Shiseido Haku Melanofocus V Brightening Serum — 45 g
Shiseido Haku Melanofocus V is Japan's most advanced brightening serum from Shiseido's iconic whitening research programme. Formulated with the dual active complex of 4-Methoxysalicylic Acid (4MSK) and Tranexamic Acid — both classified as quasi-drug whitening agents in Japan — it targets melanin production at multiple points in the pigmentation process. The new V-Cut Complex (white lily extract, glucosamine HCl, glucosamine) enhances skin penetration and provides additional moisture support. Covers approximately 2.5 months of use. A benchmark product for brightening-focused Japanese skincare.
Explore the full Shiseido collection and brightening serums at Tsujimoto Market.
Key Benefits
- ✓ 4-Methoxysalicylic Acid (4MSK) — Shiseido's proprietary quasi-drug whitening agent that inhibits melanin synthesis within the skin
- ✓ Tranexamic Acid — a second quasi-drug whitening active that blocks the melanocyte-stimulating signal at the skin surface level
- ✓ Dual-pathway approach: addresses pigmentation from both the signal (tranexamic acid) and synthesis (4MSK) stages
- ✓ V-Cut Complex (white lily extract + glucosamine) enhances ingredient penetration and maintains optimal skin moisture
- ✓ Light yet rich texture absorbs quickly without heaviness; suitable for layering under moisturiser and sunscreen
- ✓ Classified as a quasi-drug (医薬部外品) in Japan — a higher regulatory standard than standard cosmetics
- ✓ One bottle covers approximately 2.5 months at twice-daily use
- ✓ Authentic Shiseido Japan domestic version, ships from Kobe, Japan
Product Details
| Field | Value |
|---|---|
| Brand | Shiseido |
| Product Name (EN) | Haku Melanofocus V Brightening Serum |
| Product Name (JP) | 資生堂 ハク メラノフォーカスV |
| Category | Skincare |
| Subcategory | Serum |
| Product Type | Serum (pump dispenser) |
| Net Content | 45 g (approx. 2.5 months at twice-daily use) |
| Quasi-Drug Status | Yes — 医薬部外品 (approved whitening active ingredients under Japanese pharmaceutical regulations) |
| Country of Origin | Japan |
| Skin Type / Target User | All skin types; especially skin with dark spots, uneven tone, or sun damage |
| Main Concerns | Dark spots, freckles, uneven skin tone, post-inflammatory pigmentation, sun damage |
| Key Ingredients | 4-Methoxysalicylic Acid (4MSK), Tranexamic Acid, White Lily extract, Glucosamine HCl |
Who Is This For?
- ✓ Anyone dealing with persistent dark spots, freckles, or melasma who wants clinically validated whitening actives
- ✓ Women 30+ experiencing sun-related pigmentation or uneven skin tone that standard vitamin C serums have not resolved
- ✓ Those who want the highest regulatory standard for whitening (quasi-drug) backed by Shiseido's decades of melanin research
- ✓ Skincare enthusiasts who value a Japan-exclusive formulation not available in the same form internationally
How to Use
- Use every morning and evening after cleansing and toning.
- Dispense 2 pumps onto palm.
- Apply to 5 points: both cheeks, forehead, nose, and chin.
- Spread from the centre of the face outward, focusing on areas of concern (dark spots, uneven tone).
- Follow with your regular moisturiser. Always apply SPF in the morning — whitening serums require sun protection to prevent reversal of brightening results.
Amount: 2 pumps, twice daily
Frequency: Morning and evening
Tip: Consistent daily use for a minimum of 8 weeks is recommended for visible brightening of existing dark spots. Use a broad-spectrum SPF 30+ every morning for best results.
Ingredients
Active quasi-drug whitening ingredients: 4-Methoxysalicylic Acid Potassium Salt (4MSK), Tranexamic Acid.
Base ingredients include: Water, glycerin, butylene glycol, white lily (Lilium candidum) extract, glucosamine HCl, dimethicone, PEG-type emulsifiers, carbomer, phenoxyethanol, parfum.
Note: Full INCI list not published by Shiseido Japan for this quasi-drug formulation. Active ingredients verified via RatzillaCosme and crossshelf.com. Verify with product label for complete information.
Cautions
- For external use only. Keep away from eyes; rinse thoroughly if contact occurs.
- Perform a patch test before first use on a small area of skin.
- Discontinue use if redness, swelling, or irritation develops.
- Always apply a broad-spectrum SPF 30+ sunscreen in the morning when using whitening actives — UV exposure can reverse and worsen pigmentation.
- Consult a dermatologist before use if pregnant, nursing, or if you have a skin condition.
- Keep out of reach of children.
- Store at room temperature, away from direct sunlight.
- Use by the best-before date on the packaging.
Package Contents
- 1 × Shiseido Haku Melanofocus V Serum (45 g, pump dispenser)
Shipping & Store Notes
- Ships directly from Japan
- Processing time: 2–6 business days
- Tracking number provided after dispatch
- Import duties and taxes may apply depending on destination country
- Opened cosmetics cannot be returned for hygiene and safety reasons
Authenticity Guarantee
Every product at Tsujimoto Market is sourced directly from Japan and verified for authenticity. We never sell fakes or grey-market goods. Each order is carefully packed and dispatched with full tracking.
FAQ
What is quasi-drug status and why does it matter?
In Japan, quasi-drugs (医薬部外品) are products with active ingredients that have passed regulatory review by the Ministry of Health, Labour and Welfare (MHLW) for specific efficacy claims — including whitening. This is a higher standard than standard cosmetics and means the active ingredients (4MSK and tranexamic acid) are verified to have a whitening effect, not just claimed to.
What is the difference between Melanofocus V and previous versions?
The V version introduced the V-Cut Complex (white lily extract + glucosamine), which enhances penetration of the core whitening actives. Previous iterations relied on 4MSK alone; the dual-active approach targeting both surface signals and deeper melanin synthesis is specific to the V formulation.
How long will it take to see results?
Most users observe the first visible improvement in skin luminosity after 4–6 weeks of consistent twice-daily use. For existing dark spots and melasma, 8–12 weeks is the typical evaluation window. Results are dependent on daily SPF protection — skipping sunscreen will reverse progress.
Is this the Japanese domestic version?
Yes. This is the Shiseido Haku product sold in Japan, not the international (global) Shiseido whitening serum. The Haku line uses quasi-drug actives (4MSK + tranexamic acid) that differ from the internationally marketed formulation.
Can I use this if I have sensitive skin?
4MSK is generally well tolerated. However, those with very sensitive or compromised skin barrier should patch-test first. Start with once-daily use and increase to twice daily after 1–2 weeks if there is no irritation.